Friday, October 9, 2026
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Iran and Latin America: An alliance of convenience

by the El Reportero’s news services

Mahmoud AhmadinejadMahmoud Ahmadinejad

Iran has mounted a concerted and successful diplomatic outreach towards Latin America designed to counter U.S. interests and offset the pressure it is facing over its alleged nuclear enrichment ambitions. President Mahmoud Ahmadinejad, a controversial figure both at home and abroad, has found a welcome in capitals from La Paz to Caracas that he cannot be sure of anywhere else.

The promise of Iranian investment has helped to bolster its political initiatives, yet there remains a large gap between the hype surrounding its promise of broad anti-imperialist cooperation and the reality of funds left unspent and projects unimplemented. Tehran’s major challenge is to effect a coherent long-term strategy towards Latin America that goes beyond the opportunism of its recent contacts. The close personal relationship between Venezeula’s President Hugo Chávez and Ahmadinejad has made Caracas the most important port of call for Iran. Yet it is Brazil’s biggame diplomacy that may, in the long-term, offer Tehran the best opportunities to leverage its political and economic clout.

Rebels kidnap Colombian governor

On 21 December the governor of the southern province of Caquetá was kidnapped from his home by gunmen dressed in military uniforms, in an attack the authorities believe was carried out by the Fuerzas Armadas Revolucionarias de Colombia (Farc) guerrilla group.

This would be the Farc’s fi rst major stunt since early 2009 and arguably its most high profile kidnapping since 2002. The stunt is a bold show of strength intended to demonstrate that the rebel group is not a spent force ahead of important congressional and presidential elections in March and May next year. The attack, in the context of increased activity by the group in the latter part of 2009, appears to indicate that it has come out of a strategic withdrawal following its disastrous year in 2008.

Venezuela: Campaign to Revoke Obama´s Nobel

The United Socialist Party of Venezuela (PSUV) shapes from Tuesday a world campaign to claim the revocation of the Nobel Peace Prize that was bestowed upon Barack Obama because he is considered to be a warmonger.

was founded in 1901 andAccording to the party, which has more that seven million members, the first African American Head of the White House is far from deserving the prize that has been bestowed upon 95 people and 20 organizations.

We believe there should be a review of the acknowledgement. It is a duty of the progressive countries to request it, assured leader of the PSUV Jacqueline Faria when she announced the initiative.

According to Faria, the Commission of Foreign Affairs of the bloc has the mission to promote the crusade.

The justification of the war in Afghanistan, the sending of new occupying troops to that Central Asian nation and the installation of military stations in Colombia and Panama constitute arguments to demand the annulment of the Nobel Prize.

Obama´s stance at the Summit on Climate Change in Copenhagen, where he acted as a strategist but a war one, should be added to that.

Faria recalled the North American plan of imposing an exclusive pact in the meeting that was meant to save the planet, which was a proposal with a lack of concrete actions to move forward in the mitigation of the release of pollutant gases to the atmosphere that are responsible for the increase of global temperature.

Obama has broken his promises of peace and change, she said.

Among the guests that are different from Obama are the indigenous Guatemalan Rigoberta Menchu (1992), Kenyan environmentalist and politician Wangari Maathai (2004), former President of the United States James Carter (2002) and former US Vice President Al Gore (2007).

­(Latin News and Prensa Latina contributed to this report).

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College graduation gap continues to expand

by Malkia Cyril, y co-autores

A major new report on higher education has found that Hispanics and African Americans are completing college at rates far below those of their white counterparts.

The study also revealed that rates of non-white and low-income students receiving bachelor’s degrees have seen little increase over the past 30 years. The analysis was released by the Access to Success (A2S) Initiative, a project run by the heads of the 24 U.S. college and university systems with support from The Education Trust, a national organization that works to promote academic achievement.

A2S was formed in 2007 with goals of increasing the number of college-educated adults and ensuring that their institutions of higher education graduated more students of color and those from families in the lowest- income brackets.

Their report, “Charting a Path,” culls data from a baseline survey of their member institutions, which according to A2S educate nearly 40 percent of undergraduates at four-year colleges and universities nationwide. Survey results clearly show that non-white and low-income young adults are having far more difficulty receiving their degrees than are white students. While 36 percent of white young adults are attaining a bachelor’s degree, the rate is only 20 percent for blacks and 12 percent for Latinos.

Once in college, students of color are much less likely than their white counterparts to graduate. An estimated six in ten white students earn bachelor’s degrees within six years, compared with only about four in ten students of color.

The report also found that the gaps separating Latino and African-American students from their white peers are wider today than in 1975. Thirty years ago, 24 percent of white young adults attained a bachelor’s degree, a figure more than double that of blacks (11 percent) and two and a half times that of Latinos (9 percent). at rate (20 percent), with Latinos at one-third (12 percent). Latinos have seen only a 3 percent growth in degree attainment over the last 30-plus years.

The differences between high- and low-income students are even more apparent.

In 1975, 38 percent of high-income young adults attained a bachelor’s degree, compared to 7 percent of their low-income classmates. Today, a staggering 76 percent of high-income young adults are receiving a four-year degree, contrasted to only 10 percent of those from low-income families.

A2S participants claim these disparities cannot be corrected until policymakers have access to data that better reflect the attendees and graduates of colleges and universities. According to A2S, unlike in their study, transfer and part-time students aren’t included in federal data collections, nor is the progress of low-income students tracked through college.

However, these previously uncounted students account for two-thirds of students in the A2S Initiative and a similar percentage of higher education enrollments nationwide.

“Students who aren’t counted don’t count when policies are debated and decisions are made,” said Jennifer Engle, assistant director of higher education at The Education Trust and coauthor of the report. “By measuring results for such nontraditional groups as low-income, transfer and part-time students, the A2S metrics provide an unprecedented view of how well institutions are serving their entire undergraduate enrollment, not just a select few.”

Each of the A2S participant-institutions sets its own progress goals for increasing graduation rates among targeted communities, but the organization is working collectively to achieve the goal of halving by 2015 the gaps in college-going and college-completion that separate low-income and non-white students from the others.

“Closing the achievement gap is not just a competitiveness issue for our nation. It is also the civil rights issue of our day,” said William E. Kirwan, chancellor of the University System of Maryland.

A2S hopes to pressure national leaders on the issue by invoking the struggling economy and promises made by President Obama. A press release announcing the survey results states, “President Obama seta goal for America to regain the global lead in college-degree attainment by 2020. In no small measure, our success in meeting this goal — and in helping our once-vital economy rebound to generate more job opportunities for all Americans — will depend on higher education leaders taking responsibility for making colleges work better for all of the students they serve.” Hispanic Link.

Details of the study can be found at: ­http://www.edtrust.org/sites/edtrust.org/files/publcations/files/NASH-EdTrust.BaselineReport.pdf.

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Great Latino musicians exceed in non-latino jazz category this year

por Antonio Mejías-Rentas

Paquito D’RiveraPaquito D’Rivera

DOUBLE NOMINEES: Two Caribbean jazz instrumentalists are up for Grammy Awards in non-Latin categories this year.

­Cuban saxophonist Paquito D’Rivera is up for separate awards in composition and classical categories for recordings with his Paquito D’Rivera Quintet. Borat in Syracuse is up for Best Instrumental Composition; it is a track from Jazz-Class, which competes for the Best Classical Crossover Album.

A past Grammy winner, D’Rivera is also metioned for his contribution to another album nominated in the classical crossover category: Yo-Yo Ma & Friends: Songs of Joy and Peace.

Puerto Rican saxophone player Miguel Zenón earned nominations in two jazz categories for his album Esta Plena. The track Villa Palmeras is up in the Best Improvized Jazz Solo category, while the album is nominated in the Best Latin Jazz category.

Other nominees for Best Latin Jazz Album where Chambo Corniel with Things I Wanted to Do,” Geoffrey Keezer with Áurea, Claudio Roditi with “Brazilian X 4” and the father-and-son team of Bebo Valdés and Chucho Valdés with Juntos para siempre.

Two other Latino musicians were nominated in classical categories. Peruvian tenor Juan Diego Flórez is nominated for Best Classical Vocal Performance for Bel Canto Spectacular and Puerto Rican composer Roberto Sierra is up for Best Classical Contemporary Composition for his Missa Latina ‘Pro Pace’.

Nominees in the seven Latin music categories included several winners at last month’s Latin Grammy Awards, including Puerto Rican duo Calle 13, Mexican ranchera superstar Vicente Fernández, Cuban songstress Omara Portuonpordo and Nicaraguan salsero Luis Enrique.

Grammy nominees were announced last month in Los Angeles, where the awards will be given in January.

In other music award news, bachata superstar group Aventura has seven nominations for the Premio Lo Nuestro announced this month by Univisión. The network has opened public voting on its website through December and will hand out awards in February.

ONE LINER: Sin nombre, Cary Fukunaga’s fi lm about Central America immigrants making a dangerous trek to the United States, has been nominated in the Best Film category for the Spirit awards…Hispanic Link.

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Domestic workers launch national campaign for better working conditions

Compiled by the El Reportero’s staff

Domestic workers around the county are uniting in a campaign to create international labor standards for domestic work through the passage of an ILO (International Labor Organization) Convention on Domestic Work.

“Domestic workers (housecleaners, nannies, and elderly care givers) are left out of most basic labor protections and as a result are left vulnerable to abuse and exploitation on the job,” said a written statement released by the leadership of Mujeres Unidas y Activas in San Francisco.

Domestic workers are excluded from or discriminated against by most labor and employment laws, adds the document, affirming that domestic worker’s exclusion from the National Labor Relations Act, means they are unprotected when asking for respect of their basic rights and are unable to collectively bargain for conditions allowing them to labor in dignity.

In the U.S. domestic workers are not only organizing to win an ILO Convention, they are also advocating in state and federal government.

Hotel workers start boycott of Westing Hotel

Hotel workers take to the streets this morning at the W hotel, launching another boycott of a San Francisco hotel. Hundreds of workers are expected to participate in this two-day informational picket, ending Thursday at 10:00 p.m.

Today’s action comes as hotel management companies continue to press for a contract that would slash health and retirement benefits and would increase workloads. “We’ve proposed the cheapest contract in the union’s history while the corporations continue to make millions in profi ts,” said John Elrod, bartender at the W Hotel since it opened in 1999. “I think the hotel workers have sacrifi ced enough.”

In July 2009, the W Hotel was bought by Asian conglomerate, Keck Seng for $90 million or about $223,000 per room. The W is managed by Starwood Hotels & Resorts [NYSE: HOT], the same company that manages the Palace, St. Francis, and St. Regis hotels. Starwood earned $180 million in profits during the fi rst nine months of this year, and its stock price has risen 66% since January 1.

The union has indicated a willingness to settle for a contract that would result in as little as a 1.5% increase in payroll costs – or less than $140,000 for the W.

­“There has never been a question of whether they can afford what’s on the table,” said Mike Casey, President of Local 2. “The question is whether these companies will make a business decision that’s in the best interests of workers, the City, and the hotels themselves.”

Activist truck was vandalized CodePINK Women for Peace truck was attacked and damaged early Sunday last week.

According to a An unidentified white male took what appeared to be a sledge hammer several times to the front wind-shield, the side and rear view mirrors and frame, and the passenger side window, shattering glass and bending the frame.

CodePINK activists reported they were not surprised by this increase in violence, indicating it corresponds with the increase of violence against Afghanistan and claiming that the violence of war cannot be contained to what they called “U.S. defi ned ‘war zones’”.

“The increased violence of the U.S. military ‘surge’ against Afghanistan as directed by President Obama, reverberates throughout the planet and this local vandalism is merely a refl ection of the vibration of violence entering our everyday life,” says CodePINKer Grace Severtson.

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Major new study shows Hispanic, Black college students failing further behind

by Erick Galindo

A major new report on higher education has found that Hispanics and African-Americans are completing college at rates far below those of their white counterparts. The study also revealed that rates of non-white and low-income students receivaing bachelor’s degrees have seen little increase over the past 30 years.

The analysis was released by the Access to Success (A2S) Initiative, a project run by the heads of the 24 U.S. college and university systems with support from The Education Trust, a national organization that works to promote academic achievement. A2S was formed in 2007 with goals of increasing the number of college-educated adults and ensuring that their institutions of higher education graduated more students of color and those from families in the lowest-income brackets.

Their report, “Charting a Path,” culls data from a baseline survey of their member institutions, which according to A2S educate nearly 40 percent of undergraduates at four-year colleges and universities nationwide.

Survey results clearly show that non-white and low-income young adults are having far more difficulty receiving their degrees than are white students. While 36% of white young adults are attaining a bachelor’s degree, the rate is only 20% for blacks and 12% for Latinos. Once in college, students of color are much less likely than their white counterparts to graduate. An estimated six in ten white students earn bachelor’s degrees within six years, compared with only about four in ten students of color.

The report also found that the gaps separating Latino and African-American students from their white peers are wider today than in 1975. Thirty years ago, 24% of white young adults attained a bachelor’s degree, a figure more than double that of blacks (11%) and two and a half times that of Latinos (9%).

Today, white young adults are receiving degrees at a rate of 36%, Blacks are doing so at barely half that rate (20%), with Latinos at one-third (12%). Latinos have seen only a 3% growth in degree attainment over the last 30-plus years.

The differences between high- and low-income students are even more apparent. In 1975, 38% of high-income young adults attained a bachelor’s degree, compared to 7% of their low-income classmates. A staggering 76% of highincome young adults receiving a four-year degree, contrasted to only 10% of those from low-income families.

A2S participants claim these disparities cannot be corrected until policymakers have access to data that better refl ect the attendees and graduates of colleges and universities. According to A2S, unlike their study, transfer and part-time students aren’t included in federal data collections, nor is the progress of lowincome students tracked through college.

However, these previously uncounted students account for two-thirds of ­students in the A2S Initiative and a similar percentage of higher education enrollments nationwide.

“Students who aren’t counted don’t count when policies are debated and decisions are made,” said Jennifer Engle, assistant director of higher education at The Education Trust and coauthor of the report.

“By measuring results for such nontraditional groups as low-income, transfer and part-time students, the A2S metrics provide an unprecedented view of how well institutions are serving their entire undergraduate enrollment, not just a select few.”

Each of the A2S partici- pant-institutions sets its own progress goals for increasing graduation rates among targeted communities, but the organization is working collectively to achieve the goal of halving by 2015 the gaps in college-going and college-completion that separate low-income and non-white students from the others.

“Closing the achievement gap is not just a competitiveness issue for our But he neglected his health.

“And yes, he was strong, but he couldn’t understand that his body had a (health) condition, which if it went untreated by a doctor, it would kill him before his wishes,” Mrs. Vides said.

“The pain that I feel today in my heart, is because I will not be able to listen to him telling me how happy he was in the house that he decorated with such love for me,” Mrs. Vides said.

“I was just with him… he (Mr. Vides) was a type of person that even when I hadn’t seem for several weeks, he would greed you as if he hadn’t seen you for one day,” said Jake Pavlovsky, board president of Mission Neighborhood Centers.

Mr. Vides, born on Aug. 20, 1945 in San Salvador, came to San Francisco in 1972. When he went to eat at El Zocalo Restaurant, which was owned by Mrs. Vides’s aunt and uncle, he met Victoria. “My aunt liked him, so one of those days when I went to help them at the restaurant, they introduced us,” said Mrs. Vides to El Reportero. They got married in Sept. 28, 1974, at St. Anthony’s Church. Soon after, when the aunt nation. It is also the civil rights issue of our day,” said William E. Kirwan, chancellor of the University System of Maryland.

A2S hopes to pressure national leaders on the issue by invoking the struggling economy and promises made by President Obama. A press release announcing the survey results states, “President Obama set a goal for America to regain the global lead in college-degree attainment by 2020. In no small measure, our success in meeting this goal — and in helping our once-vital economy rebound to generate more job opportunities for all Americans — will depend on higher education leaders taking responsibility for making colleges work better for all of the students they serve.” Hispanic Link News Service.

(Erick Galindo, based in Washington, D.C., is editor of Hispanic Link News Service. Email: erick.geee@gmail.com) Details of the study can be found at: http://www.edtrust.org/sites/edtrust.org/files/publications/fi les/NASH-EdTrust.BaselineReport.pdf.

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VacciNation: Duped by medical quackery

­Marvin  J. RamírezMarv­in R­amír­ez­­­­­­

NOTE FROM THE EDITOR: As our government manipulated by the banking elite consolidates its power in its pursuit to enslaving us all, both are trying in many convincing ways to make us or force us to take the deadly vaccine H1N1 against the swine flu. I found the following article very informative and suggest that all of you read it and make your own determination about rejecting the H1N1 vaccine. Please share it.

 

by Anthony Gucciardi, Infowars

Vaccinations are pushed by the news media and other so-called experts as the miracle cure to a variety of conditions, but have you ever examined the science for yourself? Would the very suggestion that vaccinations are harmful incite anger inside of you, causing you to dismiss this article as hogwash? If vaccinations are truly the silver bullet against deadly diseases, and their safety is indeed based upon concrete science, then there should be no fear as to investigating the matter further. Read more below.

Why then, is mainstream media along with many medical establishments refusing to discuss the science behind vaccinating to a proficient degree? You could argue that it’s “so stupid that they don’t want to waste their time on it”, but if that were the case then why are so many doctors exposing the health hazards of vaccines? Even if it so so stupid that it made absolutely no sense, wouldn’t the mainstream media pick it up to get higher ratings? Wouldn’t the “loonies” bring some viewers to their station, to laugh at their “insanity”?

The research is out there

Lymphadenitis DevelopingVaccines and Immunization References and Research Citations Vaccines Have Been Linked to Leukemias and Lymphomas: Bichel, “Post-vaccinial into Hodgkin’s Disease”, Acta Med Scand, 1976, Vol 199, p523-525. Stewart, AM, et al, “Aetiology of Childhood Leukaemia”, Lancet, 16 Oct, 1965, 2:789-790.

[Listed under Vaccine Adverse Reactions.] Glathe, H et al, “Evidence of Tumorigenic Activity of Candidate Cell Substrate in Vaccine Production by the Use of Anti-Lymphocyte Serum”, Development Biol Std, 1977, 34:145-148.

These are but a few of the studies. This is not a complete list. Thimerosal (Mercury) is a toxic additive.

Even if vaccinations were effective outside the realm of additives, they would still be harmful. The title of the toxic additive may have changed from “mercury” to “thimerosal”, but it’s effects have stayed the same. If you don’t believe that thimerosal is in the vaccination, then why don’t you take a look at the insert tab for the seasonal flu vaccine. Perhaps the most disturbing fact is that thimerosal is not the only additive. The other additives might churn your stomach.

Other additives: aluminum hydroxide aluminum phosphate ammonium sulfate amphotericin B calf (bovine) serum animal tissues: pig blood, horse blood, rabbit

brain, dog kidney, monkey kidney, chick embryo, chicken egg, duck egg betapropiolactone fetal bovine serum formaldehyde formalin gelatin glycerol human diploid cells (originating from human aborted fetal tissue) hydrolized gelatin This is not a complete list. This is but an excerpt from the Physician’s Warranty of Vaccine Safety, which is actually supposed convince people that vaccines are good for you.

Disapproval of the truth

With kids being offered pizza to take the deadly swine fl­u vaccine, it’s easy to see that vaccinations are not being suggested, but instead we are being pushed to take them as if it were immoral to object.

The mainstream media acts as if everyone who rejects their vaccination will infect everyone else. How is this possible if the vaccinations work as claimed? If others are vaccinated, shouldn’t someone without the vaccinations be a non-issue?

Personally, I know quite a few people who received the h1n1 vaccine, yet also came down with h1n1 more than once after the fact.

Once you research the information for yourself, you come to realize that it is quite simple. Just because the mainstream media pushes it as a medical miracle does not make it so. The only way to correctly fi nd the truth in something is to investigate it. Once you go through this process you fi nd out the truth of the matter: the science behind vaccinations is fi lled with medical quackery.

 

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Boxing

Friday, Jan. 8 — at Glendale, CA (ESPN2)

  • Roman Karmazin vs. Dionisio Miranda.
  • Shannon Briggs vs. TBA.

Saturday, Jan. 9 — at Magdeburg, Germany

  • WBO super middleweight title: Robert Stieglitz vs. Edison Miranda.
  • Ina Menzer vs. Ramona Kuehne.

Monday, Jan. 11 — at Tokyo, Japan

  • WBA super featherweight title: Juan Carlos Salgado vs. Takashi Uchiyama.
  • WBA super bantamweight title: Poonsawat Kratingdaenggym vs. Satoshi Hosono.

Friday, Jan. 15 — at Laredo, TX (ESPN2)

  • ­Fernando Beltran Jr. vs. Tomas Villa.
  • Demetrius Andrade vs. TBA.
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Edgardo Vides dies, was a friend of everyone

by Marvin Ramírez

Propietario de El Zocalo y El Valenciano fallece: Edgardo ‘Edgar’ Vides, descanza en pazOwner of El Zocalo and El Valenciano dies: ‘Edgar’ Vides, rests in peace

The news of one of San Francisco Latino community’s sudden passing away of popular restaurateur , Edgar Vides, has left the Mission PiñeraDistrict and beyond in a state of shock. He was 64.

The night on Dec. 17 had a clear sky, and the chilly weather that had kept people close to their heater, indoors, had diminished. On that evening, Mr. Vides was talking to his brother Carlos, sitting down at his other El Zocalo Restaurant at El Camino Real in South San Francisco, when suddenly his head bent down forward. He was dead, instantly, and accord-ing to sources he suffered a heart attack. There was no noise or complaint.

Dozens of people, including members of Mr. Vides’s large family and friends, came to pay their respect to the family at his funeral reception at Valente Marini Perata.

Most people who knew him considered Mr. Vides a complete gentleman, a man full of joy, full of life, who always was there to talk and greet his customers personally, and one who threw a joke that made everyone laugh. He was someone special and loved. But he overworked himself, said his beloved wife.

“Edgardo always told me that he would live up to 100 years, because he was feeling stronger than a 18-year-old young man, and that he was so strong as the oak,” said his wife Victoria Vides.

But he neglected his health.

“And yes, he was strong, but he couldn’t understand that his body had a (health) condition, which if it went untreated by a doctor, it would kill him before his wishes,” Mrs. Vides said.

“The pain that I feel today in my heart, is because I will not be able to listen to him telling me how happy he was in the house that he decorated with such love for me,” Mrs. Vides said.

“I was just with him… he (Mr. Vides) was a type of person that even when I hadn’t seem for several weeks, he would greed you as if he hadn’t seen you for one day,” said Jake Pavlovsky, board president of Mission Neighborhood Centers.

Mr. Vides, born on Aug. 20, 1945 in San Salvador, came to San Francisco in 1972. When he went to eat at El Zocalo Restaurant, which was owned by Mrs. Vides’s aunt and uncle, he met Victoria. “My aunt liked him, so one of those days when I went to help them at the restaurant, they introduced us,” said Mrs. Vides to El Reportero. They got married in Sept. 28, 1974, at St. Anthony’s Church. Soon after, when the aunt and uncle put the restaurant for sale, it was an opportunity for the new wed. They decided to make an offer to purchase it, and with the help of her aunt, they took possession of their new business.

As their love grew and their restaurant consolidated, Mr. Vides got a job a Pacifi c Bell telephone company in 1975, where he worked until 10 years ago, when he retired to dedicate entirely to his other businesses.

In 1979, with the administrative skills of Mrs. Vides, they were purchased another Zocalo Restaurant in El Camino Real in San Bruno. And in 1996, an excellence opportunity arrived to purchase the El Valenciano Restaurant and its building.

Now he is gone, and with the help of “my family and my employees,” Mrs. Vides plans to continue and to maintain what she and her husband built with hard work and love.

The staff, and especially this writer, editor of El Reportero, send our very warm condolence to Mrs. Vides and the rest of the family during this diffi cult time.

Mr. Vides, whose father, José Vides is already deceased, is survived by his mother Rosaura Vides, 82; his wife of 35 years Victoria Vides, 59; four children, three daughters Roxana, Patricia and Lissette, and one son, Edgar; five grandchildren: Jonathan, Jackie, Tatiana and Mateo; and seven brothers and sisters, Vilma, sonia, María Elena, Carolina, Eraclio, José and Carlos.

 

A mass with body present will be held at Corpus Christi Church on Monday at 10:30 a.m., in San Francisco, and his remains will be taken and buried after the mass to Holy Cross Cemetery in Colma. Following, a reception will take place at El Valenciano Restaurant, at 1153 Valencia Street, San Francisco.

 

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Spices halt growth of breast stem cells

by the University of Michigan

ANN ARBOR, Mich. — A new study finds that compounds derived from the spices turmeric and pepper could help prevent breast cancer by limiting the growth of stem cells, the small number of cells that fuel a tumor’s growth.

Researchers at the University of Michigan Comprehensive Cancer Center have found that when the dietary compounds curcumin, which is derived from the Indian spice turmeric, and piperine, derived from black peppers, were applied to breast cells in culture, they decreased the number of stem cells while having no effect on normal differentiated cells.

“If we can limit the number of stem cells, we can limit the number of cells with potential to form tumors,” says lead author Madhuri Kakarala, M.D., Ph.D., R.D., clinical lecturer in internal medicine at the U-M Medical School and a research investigator at the VA Ann Arbor Healthcare System.

Cancer stem cells are the small number of cells within a tumor that fuel the tumor’s growth. Current chemotherapies do not work against these cells, which is why cancer recurs and spreads. Researchers believe that eliminating the cancer stem cells is key to controlling cancer. In addition, decreasing the number of normal stem cells – unspecialized cells that can give rise to any type of cell in that organ – can decrease the risk of cancer.

In this study, a solution of curcumin and piperine was applied to the cell cultures at the equivalent of about 20 times the potency of what could be consumed through diet. The compounds are availañoable at this potency in a capsule form that could be taken by mouth. (Note: This work has not been tested in patients, and patients are not encouraged to add curcumin or piperine supplements to their diet at this time.)

The researchers applied a series of tests to the cells, looking at markers for breast stem cells and the effects of curcumin and piperine, both alone and combined, on the stem cell levels. They found that piperine enhanced the effects of curcumin, and that the compounds interrupted the self-renewal process that is the hallmark of cancer-initiating stem cells. At the same time, the compounds had no affect on cell differentiation, which is the normal process of cell development.

“This shows that these compounds are not toxic to normal breast tissue,” Kakarala says. “Women at high risk of breast cancer right now can choose to take the drugs tamoxifen or raloxifene for prevention, but most women won’t take these drugs because there is too much toxicity. The concept that dietary compounds can help is attractive, and curcumin and piperine appear to have very low toxicity.”

Curcumin and piperine have been explored by other researchers as a potential cancer treatment. But this paper, published online in the journal Breast Cancer Research and Treatment, is the first to suggest these dietary compounds could prevent cancer by targeting stem cells.

In addition, tamoxifen or raloxifene are designed to affect estrogen, which is a factor in most, but not all breast cancers. In fact, the aggressive tumors that tend to occur more often in women with a family history or genetic suscep­tibility are typically not affected by estrogen. Because curcumin and piperine limit the self renewal of stem cells, they would impact cancers that are not estrogen sensitive as well as those that are.

Researchers are planning an initial Phase I clinical trial to determine what dose of curcumin or piperine can be tolerated in people. The trial is not expected to begin accruing participants until spring.

Breast cancer statistics: 194,280 Americans will be diagnosed with breast cancer this year and 40,610 will die from the disease, according to the American Cancer Society.

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Boxing

Friday, Nov. 28 — at Rio Rancho, NM (TeleFutura)

  • Jesus Soto Karass vs. Carlos Molina.

Saturday, Nov. 29 — at Ontario, CA (HBO)

  • IBF light middleweight title: Paul Williams vs. Verno Phillips.
  • Chris Arreola vs. Travis Walker.

Friday, Dec. 5 — at Reading, PA (TeleFutura)

  • Mike Jones vs. Luciano Perez.
  • Rock Allen vs. TBA.

Saturday, Dec. 6 — at Las Vegas, NV (HBO-PPV)

  • Oscar De La Hoya vs. Manny Pacquiao.­
  • WBO super bantamweight title: Juan Manuel Lopez vs. Sergio Medina.
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